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When a deadly viral epidemic breaks out in present-day Britain, killing hundreds of thousands of people, the government quarantines the infected behind a walled city -- only to be confronted with a resurgence of the disease 30 years in the future. In the vein of Mad Max and 28 Days Later, this morality tale veiled as a sci-fi hypothetical features enough action, combat and suspense to keep audiences wondering, "What if?"

Horror director Takashi Miike's decidedly nontraditional musical tells the story of the Katakuri clan, innkeepers who live on the depopulated slopes of Mount Fuji and who band together with tuneful Von Trapp-like determination when their guests keep turning up dead. Upon discovery of the first body, reaction shots of each family member are given the full music-video treatment … replete with dry ice and blue light!

Moments after he arrives in Spain for a landmark antiterrorism summit, U.S. President Ashton is shot. The 15 minutes leading up to the shooting are rehashed -- Rashomon-style -- from the perspective of various onlookers: two Secret Service agents (Dennis Quaid and Matthew Fox), a TV reporter (Sigourney Weaver) and a tourist (Forest Whitaker). This nail-biting political thriller marks the feature directorial debut of Pete Travis.

Based on a true story, this historical drama starring Ioan Gruffudd (Fantastic Four) tells the story of William Wilberforce, an 18th-century English politician who fought for the abolition of slavery. Despite staunch opposition, Wilberforce waged an aggressive campaign using boycotts, petitions and slogans. Director Michael Apted's (Coal Miner's Daughter) powerful film also stars Albert Finney, Michael Gambon and Rufus Sewell.

The extremely organized Lizzie Thomas (Jodhi May) is indispensable to her boss, Paul Reynolds (Damian Lewis), who, for all his brilliant ideas, would be miserably lost without her. But will his maverick style eventually tear them apart? Following the pair's 20-year working relationship from the earliest days of Thatcherism to the burst of the dot-com bubble, this thought-provoking drama paints a portrait of Britain's not-so-distant past.